Monocytes differentiated with GM-CSF and IL-15 initiate Th17 and Th1 responses that are contact-dependent and mediated by IL-15
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چکیده
منابع مشابه
GM-CSF mediates autoimmunity by enhancing IL-6–dependent Th17 cell development and survival
Granulocyte macrophage-colony stimulating factor (GM-CSF) is critically involved in development of organ-related autoimmune inflammatory diseases including experimental allergic encephalitis and collagen-induced arthritis. Roles of GM-CSF in the initiation and in the effector phase of the autoimmune response have been proposed. Our study was designed to investigate the mechanisms of GM-CSF in a...
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ژورنال
عنوان ژورنال: Journal of Leukocyte Biology
سال: 2011
ISSN: 0741-5400
DOI: 10.1189/jlb.0311132